EmbryoGlue: expensive add-on or can it really increase your chances with IVF?

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EmbryoGlue: expensive add-on or can it really increase your chances with IVF?

inFertile Life EmbryoGlue

inFertile Life EmbryoGlue

inFertile Life EmbryoGlue

When we are trying to conceive and pursuing assisted conception, there are a lot of factors that can affect our success rates. From our own mindset and ability to control the rollercoaster of emotions, to our physical health and nutrition, to treatment add-ons that we don’t know much about.

It can be difficult to do everything, not only because we would get overwhelmed and stressed but because of the financial costs involved in all these changes. So we trust the experts, trust that they know what’s best for us and what will increase our chances of success.

As a nurse, coach and infertility patient, I understand what it feels like to be on both sides.

As a nurse and coach, I want to explain available options in an unbiased way and as clearly as possible, so people can make the decision that best suits them. And as a patient, I want to know as much as possible, I want to understand the professionals’ language, and their rationale to advise that a certain treatment, intervention or add-on is what’s best for me.


One of the options available in your IVF journey is EmbryoGlue. Is it an expensive add-on or can it really increase your chances with IVF?

Let’s go by parts.

After the egg and sperm are collected and fertilized, the new embryo is placed in liquid called a culture media solution. An embryo is very fragile and developing in a petri dish is difficult! So this solution has been developed to optimise the development of the human embryo in these adverse conditions.

After the embryo has developed for a few days, it will be transferred to the uterus where it will continue to grow. Whilst normal solutions have been developed to support the embryo’s development in the petri dish, EmbryoGlue takes into account this next phase of embryo transfer and the uterine environment. It contains hyaluronan and human albumin which help the embryo to implant in the uterus.

EmbryoGlue has been in clinical use since 2003 and several studies have been done showing its effectiveness. Even though it has been shown to be effective in all patient groups, the biggest difference has been identified in:


  • Women over 35 years of age
  • Poor quality embryos
  • Previous history of implantation failure

EmbryoGlue has even been subject to two reports by The Cochrane Collaboration. This organisation looks at all research studies that have been done on a certain subject to come to a conclusion that has bigger impact. These reports reinforced the effectiveness of this solution and have noted there were no negative effects from using it.

inFertile Life EmbryoGlue chances

Another study by Dr Basak Balaban has also showed that the take-home baby rate for embryo transfer on day 5 was 63.4% using EmbryoGlue compared to 52.2% using normal solutions.

So what does this mean?

There is no doubt EmbryoGlue can help you increase your chances in clinical pregnancy, implantation rate and live birth rate. This means you will get higher chances of getting a positive pregnancy test, higher chances of your baby sticking to your uterus and higher chances of developing and being born.

Even though there are a lot of factors to consider in your fertility journey, adding up to a significant financial cost, it is worth checking which factors have been scientifically proven to work and increase your chances of success.  EmbryoGlue is worth a try, especially if you are over 35 years old, you have poor quality embryos or have a previous history of implantation failure.



Andreia Trigo (RN BSc MSc)

Fertility Nurse & NLP Coach


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